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Generation and repair of AID-initiated DNA lesions in B lymphocytes
Zhangguo Chen,Jing H. Wang
Frontiers of Medicine 2014, Volume 8, Issue 2, Pages 201-216 doi: 10.1007/s11684-014-0324-4
Keywords: class switch recombination somatic hypermutation activation-induced deaminase DNA repair genomic instability
The role of PARP1 in the DNA damage response and its application in tumor therapy
Zhifeng Wang, Fengli Wang, Tieshan Tang, Caixia Guo
Frontiers of Medicine 2012, Volume 6, Issue 2, Pages 156-164 doi: 10.1007/s11684-012-0197-3
Single-strand break repair protein poly(ADP-ribose) polymerase 1 (PARP1) catalyzes the poly(ADP-ribosyl)ation of many key proteins in vivo and thus plays important roles in multiple DNA damage responseThe present review will focus on recent progress on the role of PARP1 in the DNA damage response andresistance of BRCA-deficient tumors to PARP inhibitors is also briefly discussed from the perspective of DNAdamage and repair.
Keywords: PARP1 synthetic lethality PARP inhibitor DNA repair cancer NHEJ
Liang ZHUANG, Shiying YU, Xiaoyuan HUANG, Yang CAO, Huihua XIONG
Frontiers of Medicine 2009, Volume 3, Issue 1, Pages 26-29 doi: 10.1007/s11684-009-0008-7
Keywords: Ku80 DNA-PK(cs)-binding protein human ataxia telangiectasia mutated protein tumor cell lines radiosensitivity
Regulation and function of histone acetyltransferase MOF
Yang Yang, Xiaofei Han, Jingyun Guan, Xiangzhi Li
Frontiers of Medicine 2014, Volume 8, Issue 1, Pages 79-83 doi: 10.1007/s11684-014-0314-6
Keywords: MOF histone acetyltransferase DNA damage repair tumorigenesis embryonic stem cells
Bile duct injury repair — earlier is not better
Vinay K. Kapoor
Frontiers of Medicine 2015, Volume 9, Issue 4, Pages 508-511 doi: 10.1007/s11684-015-0418-7
Keywords: bile duct injury cholecystectomy laparoscopic cholecystectomy
Engineering DNA Materials for Sustainable Data Storage Using a DNA Movable-Type System Article
Zi-Yi Gong, Li-Fu Song, Guang-Sheng Pei, Yu-Fei Dong, Bing-Zhi Li, Ying-Jin Yuan
Engineering 2023, Volume 29, Issue 10, Pages 130-136 doi: 10.1016/j.eng.2022.05.023
DNA molecules are green materials with great potential for high-density and long-term data storageHowever, the current data-writing process of DNA data storage via DNA synthesis suffers from high costsHere, we developed a DNA movable-type storage system that can utilize DNA fragments pre-produced by cellIn this system, these pre-generated DNA fragments, referred to herein as "DNA movable types,"the costly and environmentally hazardous process of de novo DNA synthesis.
Keywords: 合成生物学 DNA信息存储 DNA活字存储系统 经济性DNA数据存储
Mobile platform for hydraulic turbine blade repair robot
GUI Zhongcheng, CHEN Qiang, SUN Zhenguo, ZHANG Wenzeng, LIU Kang
Frontiers of Mechanical Engineering 2008, Volume 3, Issue 2, Pages 164-169 doi: 10.1007/s11465-008-0035-0
Expression status of GATA3 and mismatch repair proteins in upper tract urothelial carcinoma
Yue Wang, Jinxia Zhang, Yunfan Wang, Shufang Wang, Yu Zhang, Qi Miao, Fei Gao, Huiying He
Frontiers of Medicine 2019, Volume 13, Issue 6, Pages 730-740 doi: 10.1007/s11684-019-0687-7
Keywords: upper tract urothelial carcinoma GATA binding protein 3 mismatch repair microsatellite instability prognosis
Functional role of ATM in the cellular response to DNA damage
Ming LIU, Wenxiang HU
Frontiers of Chemical Science and Engineering 2011, Volume 5, Issue 2, Pages 179-187 doi: 10.1007/s11705-009-0268-4
Keywords: ataxia-telangiectasia mutated (ATM) cell cycle checkpoint DNA damage signalling transduction
Molecular simulation of the interaction mechanism between CodY protein and DNA in
Linchen Yuan, Hao Wu, Yue Zhao, Xiaoyu Qin, Yanni Li
Frontiers of Chemical Science and Engineering 2019, Volume 13, Issue 1, Pages 133-139 doi: 10.1007/s11705-018-1737-4
Keywords: CodY DNA molecular docking molecular dynamics
Yi Cao
Frontiers of Medicine 2015, Volume 9, Issue 3, Pages 261-274 doi: 10.1007/s11684-015-0406-y
Keywords: environmental pollution DNA methylation cancer biomarker diagnosis therapy prevention
Effects of DNA damage on oocyte meiotic maturation and early embryonic development
Shen YIN,Junyu MA,Wei SHEN
Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 3, Pages 185-190 doi: 10.15302/J-FASE-2014035
Keywords: DNA damage double-strand breaks (DSBs) oocyte embryo
Single-Molecule Methods for Characterizing Different DNA Higher-Order Structures Review
Yonglin Liu, Tianyuan Bian, Yan Liu, Zhimin Li, Yufeng Pei, Jie Song
Engineering 2023, Volume 24, Issue 5, Pages 277-292 doi: 10.1016/j.eng.2022.10.009
DNA is considered to be not only a carrier of the genetic information of life but also a highly programmableDifferent DNA structures are related to their biological and chemical functions.However, the bulk assay ignores the heterogeneity of DNA structures in solution.(ss/dsDNA), DNA higher-order structures, and DNA nanostructures.methods to understand the biophysical properties of DNA and other bio-matter and soft matter.
Keywords: Single-molecule methods DNA structure Mechanical properties Conformational transitions
Yanhua GUAN, Ying GAO, Renjuan SUN, Moon C. WON, Zhi GE
Frontiers of Structural and Civil Engineering 2017, Volume 11, Issue 3, Pages 338-345 doi: 10.1007/s11709-017-0411-0
Keywords: Sulfoaluminate (CSA) cement Type III cement coefficient of thermal expansion (CTE) shrinkage rapid repair
A DNA Computing Model for the Graph Vertex Coloring Problem Based on a Probe Graph Article
Jin Xu, Xiaoli Qiang, Kai Zhang, Cheng Zhang, Jing Yang
Engineering 2018, Volume 4, Issue 1, Pages 61-77 doi: 10.1016/j.eng.2018.02.011
The biggest bottleneck in DNA computing is exponential explosion, in which the DNA molecules usedTo overcome this bottleneck and improve the processing speed, we propose a DNA computing model to solveIn this article, a 3-colorable graph with 61 vertices is used to illustrate the capability of the DNAAll these tiny strands are operated by DNA self-assembly and parallel PCR.the largest among both the electronic and non-electronic computers that have been developed since the DNA
Keywords: DNA computing Graph vertex coloring problem Polymerase chain reaction
Title Author Date Type Operation
Generation and repair of AID-initiated DNA lesions in B lymphocytes
Zhangguo Chen,Jing H. Wang
Journal Article
The role of PARP1 in the DNA damage response and its application in tumor therapy
Zhifeng Wang, Fengli Wang, Tieshan Tang, Caixia Guo
Journal Article
Correlativity study between expression of DNA double-strand break repair protein and radiosensitivity
Liang ZHUANG, Shiying YU, Xiaoyuan HUANG, Yang CAO, Huihua XIONG
Journal Article
Regulation and function of histone acetyltransferase MOF
Yang Yang, Xiaofei Han, Jingyun Guan, Xiangzhi Li
Journal Article
Engineering DNA Materials for Sustainable Data Storage Using a DNA Movable-Type System
Zi-Yi Gong, Li-Fu Song, Guang-Sheng Pei, Yu-Fei Dong, Bing-Zhi Li, Ying-Jin Yuan
Journal Article
Mobile platform for hydraulic turbine blade repair robot
GUI Zhongcheng, CHEN Qiang, SUN Zhenguo, ZHANG Wenzeng, LIU Kang
Journal Article
Expression status of GATA3 and mismatch repair proteins in upper tract urothelial carcinoma
Yue Wang, Jinxia Zhang, Yunfan Wang, Shufang Wang, Yu Zhang, Qi Miao, Fei Gao, Huiying He
Journal Article
Molecular simulation of the interaction mechanism between CodY protein and DNA in
Linchen Yuan, Hao Wu, Yue Zhao, Xiaoyu Qin, Yanni Li
Journal Article
Environmental pollution and DNA methylation: carcinogenesis, clinical significance, and practical applications
Yi Cao
Journal Article
Effects of DNA damage on oocyte meiotic maturation and early embryonic development
Shen YIN,Junyu MA,Wei SHEN
Journal Article
Single-Molecule Methods for Characterizing Different DNA Higher-Order Structures
Yonglin Liu, Tianyuan Bian, Yan Liu, Zhimin Li, Yufeng Pei, Jie Song
Journal Article
Experimental study and field application of calcium sulfoaluminate cement for rapid repair of concrete
Yanhua GUAN, Ying GAO, Renjuan SUN, Moon C. WON, Zhi GE
Journal Article